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Article

Overexpression of phage HK022 Nun protein is toxic for Escherichia coli.

Journal of molecular biology - 25 Jul 2008

Uc-Mass Augusto, Khodursky Arkady, Brown Lewis, Gottesman Max E

Abstract excerpt

The Nun protein of coliphage HK022 excludes superinfecting lambda phage. Nun recognizes and binds to the N utilization (nut) sites on phage lambda nascent RNA and induces transcription termination. Overexpression of Nun from a high-copy plasmid is toxic for Escherichia coli, despite the fact that nut sites are not encoded in the E. coli genome. Cells expressing Nun cannot exit stationary phase. Toxicity is...

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Identifiers

PMID: 18571198
DOI: 10.1016/j.jmb.2008.05.030
PMCID: PMC2597491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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