Article

Phage N4 uses a SAR endolysin-holin system for host cell lysis

2025-11-12

Abstract excerpt

Bacteriophages (phages) cause active host cell lysis to terminate their infection and release progeny into the environment. Some phages delay their lysis, and thereby increase progeny yield, in a phenomenon called lysis inhibition (LIN). There are two dissimilar phages of Escherichia coli known to exhibit LIN: T4 and N4. Studies of phage T4 have demonstrated a multi-protein mechanism that stalls lysis and maintai...

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Literature Corpus work: c16786da-803e-5be8-8d53-337061bbaca4
DOI: 10.1101/2025.11.12.688109

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