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Article

Role of E.coli NusA in phage HK022 Nun-mediated transcription termination.

Journal of molecular biology - 26 May 2006

Kim Hyeong C, Washburn Robert S, Gottesman Max E

Abstract excerpt

The 109 amino acid residue Nun protein expressed from prophage HK022 excludes superinfecting phage lambda by arresting transcription on the lambda chromosome near the lambdanut sites. In vitro, the Nun N terminus binds to nascent lambdanutRNA, whereas the C terminus interacts with RNA polymerase and DNA template. Escherichia coli host factors, NusA, NusB, NusE (S10), and NusG, stimulate Nun-arrest. NusA binds the...

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Identifiers

PMID: 16631197
DOI: 10.1016/j.jmb.2006.02.081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of E.coli NusA in phage HK022 Nun-mediated transcription termination.PMID 16631197Read ↗

Escherichia coli nusG mutations that block transcription termination by coliphage HK022 Nun protein.Semantic proximity Read ↗

Lambda nutR mutations convert HK022 Nun protein from a transcription termination factor to a suppressor of termination.Semantic proximity Read ↗

Coliphage HK022 Nun protein inhibits RNA polymerase translocation.Semantic proximity Read ↗

Phage HK022 Nun protein represses translation of phage lambda N (transcription termination/translation repression).Semantic proximity Read ↗

Overexpression of phage HK022 Nun protein is toxic for Escherichia coli.Semantic proximity Read ↗

Interactions of an Arg-rich region of transcription elongation protein NusA with NUT RNA: implications for the order of assembly of the lambda N antitermination complex in vivo.Semantic proximity Read ↗

Use of a gene encoding a suppressor tRNA as a reporter of transcription: analyzing the action of the Nun protein of bacteriophage HK022.Semantic proximity Read ↗

The Y39A mutation of HK022 Nun disrupts a boxB interaction but preserves termination activity.Semantic proximity Read ↗

NusA interaction with the α subunit of E. coli RNA polymerase is via the UP element site and releases autoinhibition.Semantic proximity Read ↗

Translational repression by a transcriptional elongation factor.Semantic proximity Read ↗

Compromised factor-dependent transcription termination in a nusA mutant of Escherichia coli: spectrum of termination efficiencies generated by perturbations of Rho, NusG, NusA, and H-NS family proteins.Semantic proximity Read ↗

Bacteriophage lambda N-dependent transcription antitermination. Competition for an RNA site may regulate antitermination.Semantic proximity Read ↗

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