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Article

Control of Pseudomonas aeruginosa in the lung requires the recognition of either lipopolysaccharide or flagellin.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2008

Ramphal Reuben, Balloy Viviane, Jyot Jeevan, Verma Amrisha, Si-Tahar Mustapha, Chignard Michel

Abstract excerpt

Acute lung infection due to Pseudomonas aeruginosa is an increasingly serious problem that results in high mortality especially in the compromised host. In this study, we set out to ascertain what components of the TLR system are most important for innate immunity to this microorganism. We previously demonstrated that TLR2,4-/- mice were not hypersusceptible to infection by a wild-type P. aeruginosa strain....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18566425
DOI: 10.4049/jimmunol.181.1.586
PMCID: PMC2504754

Genes

TLR2
TLR4
TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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