Article
The Role of Flagellin versus Motility in Acute Lung Disease Caused by<i>Pseudomonas aeruginosa</i>
18 Jun 2007
Abstract excerpt
The flagellum of Pseudomonas aeruginosa has been implicated in acute pneumonia, and its flagellin is known to cause lung inflammation. However, its proinflammatory role, versus its motility function, as a cause of death by a whole bacterium has not been demonstrated. This issue was examined in a lung model of acute infection using different flagellar mutants. We found that the absence of motility does not...
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