Article
Pseudomonas aeruginosa flagellum is critical for invasion, cutaneous persistence and induction of inflammatory response of skin epidermis.
Virulence - 1 Jan 2018
Garcia Magali, Morello Eric, Garnier Julien, Barrault Christine, Garnier Martine, Burucoa Christophe, Lecron Jean-Claude, Si-Tahar Mustapha, Bernard François-Xavier, Bodet Charles
Abstract excerpt
Pseudomonas aeruginosa, an opportunistic pathogen involved in skin and lung diseases, possesses numerous virulence factors, including type 2 and 3 secretion systems (T2SS and T3SS) and its flagellum, whose functions remain poorly known during cutaneous infection. Using isogenic mutants deleted from genes encoding each or all of these three virulence factors, we investigated their role in induction of inflammatory...
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