Differential disease restriction of Moloney and Friend murine leukemia viruses by the mouse Rmcf gene is governed by the viral long terminal repeat.

doi:10.1084/jem.174.2.389

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Article

Differential disease restriction of Moloney and Friend murine leukemia viruses by the mouse Rmcf gene is governed by the viral long terminal repeat.

The Journal of experimental medicine - 1 Aug 1991

Brightman B K, Li Q X, Trepp D J, Fan H

Abstract excerpt

Neonatal CxD2 (Rmcfr) and Balb/c (Rmcfs) mice inoculated with Moloney murine leukemia virus (M-MuLV) exhibited approximately equivalent time course and pathology for disease. CxD2 mice showed only slightly reduced presence of Moloney mink cell focus-forming virus (M-MCF) provirus as seen by Southern blot analysis compared to Balb/c mice. This lack of restriction for disease and spread of MCF was in sharp contrast...

Topics

Alleles
Animals
Blotting, Southern
Cloning, Molecular
DNA, Neoplasm
DNA, Viral
Friend murine leukemia virus
Immunity, Innate
Leukemia, Experimental
Mice
Mice, Inbred BALB C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred DBA

Moloney murine leukemia virus

Repetitive Sequences, Nucleic Acid

Retroviridae Proteins, Oncogenic

T-Lymphocytes

Viral Envelope Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 1856627
DOI: 10.1084/jem.174.2.389
PMCID: PMC2118917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1856627-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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