Article
Infection by mink cell focus-forming viruses confers interleukin 2 (IL-2) independence to an IL-2-dependent rat T-cell lymphoma line.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1991
Tsichlis P N, Bear S E
Abstract excerpt
The development of T-cell lymphomas in rodents infected with type C retroviruses has been linked to the generation of a class of envelope (env) recombinant viruses called mink cell focus-forming viruses (MCF viruses) in the preleukemic thymus. To determine whether infection by MCF viruses altered the growth phenotype of retrovirus-induced T-cell lymphomas, a Moloney murine leukemia virus-induced interleukin-2...
Topics
- Animals
- Cell Line
- Cell Survival
- Cell Transformation, Viral
- Flow Cytometry
- Genes, Viral
- Interleukin-2
- Lymphoma, T-Cell
- Mink Cell Focus-Inducing Viruses
- Moloney murine leukemia virus