Article
Susceptibility and resistance to Moloney murine leukemia virus-induced promonocytic leukemia.
Virology - 1 Dec 1994
Nazarov V, Hilbert D, Wolff L
Abstract excerpt
Moloney murine leukemia virus (M-MuLV) induces promonocytic leukemias, called MML, in pristane-treated adult mice. These tumors invariably express fused gag-myb mRNA as a consequence of virus integration and activation of the c-myb locus. In the present study it was determined that while BALB/c and DBA/2N mice are highly susceptible, C57BL/6, C3H/He, STS/A, NFS, NIH/Swiss, SJL/J, and NZB mice are strongly...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- Carcinogens
- Disease Susceptibility
- Female
- Genetic Predisposition to Disease
- H-2 Antigens
- Immunity, Innate
- Leukemia, Experimental
- Leukemia, Monocytic, Acute
