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Article

Susceptibility and resistance to Moloney murine leukemia virus-induced promonocytic leukemia.

Virology - 1 Dec 1994

Nazarov V, Hilbert D, Wolff L

Abstract excerpt

Moloney murine leukemia virus (M-MuLV) induces promonocytic leukemias, called MML, in pristane-treated adult mice. These tumors invariably express fused gag-myb mRNA as a consequence of virus integration and activation of the c-myb locus. In the present study it was determined that while BALB/c and DBA/2N mice are highly susceptible, C57BL/6, C3H/He, STS/A, NFS, NIH/Swiss, SJL/J, and NZB mice are strongly...

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PMID: 7975249
DOI: 10.1006/viro.1994.1668

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