Article
Characterization of thymic involution induced by murine cytomegalovirus infection.
Immunology and cell biology - 1 Jun 1993
Price P, Olver S D, Gibbons A E, Teo H K, Shellam G R
Abstract excerpt
Infection of BALB/c mice with murine cytomegalovirus (MCMV) decreased the numbers of cells recovered from the thymus by 80-90% after 4-7 days, although less than 10 thymocytes per million were productively infected with the virus. A loss of cortical thymocytes was evident in histologic sections a...
Topics
- Animals
- Antigens, Ly
- Atrophy
- Autoimmune Diseases
- CD4-Positive T-Lymphocytes
- Cell Adhesion Molecules
- Cell Movement
- Cytomegalovirus Infections
- Genetic Predisposition to Disease
- H-2 Antigens
- Immunophenotyping
- Interleukin-3
- L-Selectin
- Leukocyte Count
- Lymphocyte Activation
- Macrophage-1 Antigen
- Membrane Proteins
- Mice