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Article

An enhancer variant of Moloney murine leukemia virus defective in leukemogenesis does not generate detectable mink cell focus-inducing virus in vivo.

Proceedings of the National Academy of Sciences of the United States of America - 15 Mar 1991

Brightman B K, Rein A, Trepp D J, Fan H

Abstract excerpt

Moloney murine leukemia virus (Mo-MuLV) induces T-cell lymphoma when inoculated into neonatal mice. This is a multistep process. Early events observed in infected mice include generalized hematopoietic hyperplasia in the spleen and appearance of mink cell focus-inducing (MCF) recombinants; end-stage tumors are characterized by insertional proviral activation of protooncogenes. We previously showed that an Mo-MuLV...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 2006167
DOI: 10.1073/pnas.88.6.2264
PMCID: PMC51211

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Source receipt: pubmed, retrieved 7 Sept 2026.

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