Article
An enhancer variant of Moloney murine leukemia virus defective in leukemogenesis does not generate detectable mink cell focus-inducing virus in vivo.
Proceedings of the National Academy of Sciences of the United States of America - 15 Mar 1991
Brightman B K, Rein A, Trepp D J, Fan H
Abstract excerpt
Moloney murine leukemia virus (Mo-MuLV) induces T-cell lymphoma when inoculated into neonatal mice. This is a multistep process. Early events observed in infected mice include generalized hematopoietic hyperplasia in the spleen and appearance of mink cell focus-inducing (MCF) recombinants; end-st...
Topics
- Animals
- Cell Line
- Cell Transformation, Neoplastic
- Defective Viruses
- Enhancer Elements, Genetic
- Genetic Variation
- L Cells
- Leukemia, Experimental
- Mice
- Mink Cell Focus-Inducing Viruses
- Moloney murine leukemia virus
- Preleukemia
- Proviruses