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Article

Genetic variation in insulin-like growth factors and brain tumor risk.

Neuro-oncology - 1 Aug 2008

Lönn Stefan, Rothman Nathaniel, Shapiro William R, Fine Howard A, Selker Robert G, Black Peter M, Loeffler Jay S, Hutchinson Amy A, Inskip Peter D

Abstract excerpt

Many studies support a role for insulin-like growth factors (IGFs) in the regulation of tumor cell biology. We hypothesized that single-nucleotide polymorphisms (SNPs) in IGF genes are risk factors for glioma and meningioma. To test the hypothesis, we examined associations of brain tumor risk with nine variants in five IGF genes in a hospital-based case-control study. The study was conducted at hospitals in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18562769
DOI: 10.1215/15228517-2008-026
PMCID: PMC2666228

Genes

IGF1
IGF2
IGFBP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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