Influence of obesity-related risk factors in the aetiology of glioma.

doi:10.1038/s41416-018-0009-x

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Article

Influence of obesity-related risk factors in the aetiology of glioma.

British journal of cancer - 1 Apr 2018

Disney-Hogg Linden, Sud Amit, Law Philip J, Cornish Alex J, Kinnersley Ben, Ostrom Quinn T, Labreche Karim, Eckel-Passow Jeanette E, Armstrong Georgina N, Claus Elizabeth B, Il'yasova Dora, Schildkraut Joellen, Barnholtz-Sloan Jill S, Olson Sara H, Bernstein Jonine L, Lai Rose K, Swerdlow Anthony J, Simon Matthias, Hoffmann Per, Nöthen Markus M, Jöckel Karl-Heinz, Chanock Stephen, Rajaraman Preetha, Johansen Christoffer, Jenkins Robert B, Melin Beatrice S, Wrensch Margaret R, Sanson Marc, Bondy Melissa L, Houlston Richard S

Abstract excerpt

BACKGROUND: Obesity and related factors have been implicated as possible aetiological factors for the development of glioma in epidemiological observation studies. We used genetic markers in a Mendelian randomisation framework to examine whether obesity-related traits influence glioma risk. This methodology reduces bias from confounding and is not affected by reverse causation. METHODS: Genetic instruments were...

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PMID: 29531326
DOI: 10.1038/s41416-018-0009-x
PMCID: PMC5931112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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