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Article

IGF2R missense single-nucleotide polymorphisms and breast cancer risk: the multiethnic cohort study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2009

Cheng Iona, Stram Daniel O, Burtt Noël P, Gianniny Lauren, Garcia Rachel R, Pooler Loreall, Henderson Brian E, Le Marchand Loïc, Haiman Christopher A

Abstract excerpt

IGF2R has been proposed to be a tumor suppressor gene given its antagonist role on cellular growth and evidence of loss of heterozygosity in several cancers, including breast cancer. To investigate whether inherited differences in potentially functional IGF2R variants influence the risk of breast cancer, we sequenced 46 exons of IGF2R to identify novel missense single-nucleotide polymorphisms (SNP) and tested 12...

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Identifiers

PMID: 19435860
DOI: 10.1158/1055-9965.EPI-09-0253
PMCID: PMC2878205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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