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Article

Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma.

Journal of neuro-oncology - 1 Nov 2017

Zhang Chenan, de Smith Adam J, Smirnov Ivan V, Wiencke John K, Wiemels Joseph L, Witte John S, Walsh Kyle M

Abstract excerpt

Although genome-wide association studies have identified several susceptibility loci for adult glioma, little is known regarding the potential contribution of genetic variation in the human leukocyte antigen (HLA) region to glioma risk. HLA associations have been reported for various malignancies, with many studies investigating selected candidate HLA polymorphisms. However, no systematic analysis has been...

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Identifiers

PMID: 28721485
DOI: 10.1007/s11060-017-2569-7
PMCID: PMC5665694

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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