Article
Brain tumor risk according to germ-line variation in the MLLT10 locus.
European journal of human genetics : EJHG - 1 Jan 2015
Egan Kathleen M, Baskin Rebekah, Nabors L Burton, Thompson Reid C, Olson Jeffrey J, Browning James E, Madden Melissa H, Monteiro Alvaro N
Abstract excerpt
Genome-wide association studies have recently identified a cancer susceptibility locus at 10p12 mapping to MLLT10 associated with the onset of diverse tumors. We genotyped two tightly linked single-nucleotide polymorphisms (SNPs) at MLLT10 associated with meningioma (rs12770228) or ovarian cancer (rs1243180), and tested for associations among 295 meningioma cases, 606 glioma cases and 646 noncancer controls, all...
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