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Article

Genetic variants in IGF2BP family genes are associated with glioma risk in Chinese children.

Molecular medicine (Cambridge, Mass.) - 16 Jun 2026

Su Yuling, Liao Yuxiang, Yuan Li, Wang Linqian, Liu Jiabin, Zhou Haixia, Wang Tianyou, He Jing

Abstract excerpt

BACKGROUND: Glioma is a highly prevalent malignant tumor of the central nervous system in children and is driven by complex genetic and environmental factors. IGF2BP family genes (IGF2BP1, IGF2BP2, and IGF2BP3) encode critical RNA epigenetic "readers" that participate in posttranscriptional gene regulation and modulate various cellular processes. However, the contributions of these gene variants to glioma risk...

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Brain Neoplasms
China
East Asian People
Glioma
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quantitative Trait Loci

RNA-Binding Proteins

Source

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Identifiers

PMID: 42298413
DOI: 10.1186/s10020-026-01527-z
PMCID: PMC13504984

Genes

IGF2BP1
IGF2BP2
CALCOCO2
IGF2BP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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