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Article

Biochemical characterization of the WRN-1 RecQ helicase of Caenorhabditis elegans.

Biochemistry - 15 Jul 2008

Hyun Moonjung, Bohr Vilhelm A, Ahn Byungchan

Abstract excerpt

The highly conserved RecQ helicases are essential for the maintenance of genomic stability. Werner syndrome protein, WRN, is one of five human RecQ helicase homologues, and a deficiency of the protein causes a hereditary premature aging disorder that is characterized by genomic instability. A WRN orthologue, wrn-1 lacking the exonuclease domain, has been identified in the nematode Caenorhabditis elegans....

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Share to Adenosine Triphosphatases
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Source

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Identifiers

PMID: 18558712
DOI: 10.1021/bi800197m
PMCID: PMC2583433

Genes

WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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