Article
Haplotype analysis of the MDR1 flanking region in the dog breed Elo.
Berliner und Munchener tierarztliche Wochenschrift - 1 Jan 2000
Fecht Silvia, Wöhlke Anne, Distl Ottmar
Abstract excerpt
A deletion mutation in the canine multidrug resistance (MDR1) gene provokes drug sensitivity in several dog breeds from the Collie lineage. A haplotype of four microsatellites containing this mdr1-1Delta mutation was conserved among affected breeds. In this study, we analysed the haplotypes of the MDR1 flanking region of 177 dogs of the breed Elo which is composed of several dog breeds including the Old English...
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