Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the canine mdr1-1Delta mutation in the dog breed Elo.

Journal of veterinary medicine. A, Physiology, pathology, clinical medicine - 1 Oct 2007

Fecht S, Wöhlke A, Hamann H, Distl O

Abstract excerpt

A deletion mutation in the canine multidrug resistance gene, MDR1, is associated with drug sensitivity. This was shown for several purebred dog breeds from the Collie lineage such as the Collie (rough-coated and smooth-coated), the Australian Shepherd and the Old English sheepdog. To determine whether the mdr1-1Delta mutation could be found in the newly bred German dog breed Elo which is based amongst other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to Breeding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dog Diseases

Share to Drug Resistance, Multiple

Share to Genes, MDR

Share to Phylogeny

Share to Sequence Deletion

Source

Identifiers

PMID: 17877579
DOI: 10.1111/j.1439-0442.2007.00966.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the canine mdr1-1Delta mutation in the dog breed Elo.PMID 17877579Read ↗

Haplotype analysis of the MDR1 flanking region in the dog breed Elo.Semantic proximity Read ↗

Breed distribution of the nt230(del4) MDR1 mutation in dogs.Semantic proximity Read ↗

Review of prevalence, genetic aspects and adverse effects of the mdr1-1Delta mutation in dogs.Semantic proximity Read ↗

Breed distribution and history of canine mdr1-1Delta, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage.Semantic proximity Read ↗

Frequency of canine nt230(del4) MDR1 mutation in prone pure breeds, their crosses and mongrels in Israel - insights from a worldwide comparative perspective.Semantic proximity Read ↗

Development of a PCR‐based diagnostic test detecting a nt230(del4) MDR1 mutation in dogs: verification in a moxidectin‐sensitive Australian ShepherdSemantic proximity Read ↗

Allele-specific polymerase chain reaction diagnostic test for the functional MDR1 polymorphism in dogs.Semantic proximity Read ↗

Detection of the nt230[del4] MDR1 mutation in dogs by a fluorogenic 5' nuclease TaqMan allelic discrimination method.Semantic proximity Read ↗

The prevalence of ABCB1:c.227_230delATAG mutation in affected dog breeds from European countries.Semantic proximity Read ↗

MDR1-deficient genotype in Collie dogs hypersensitive to the P-glycoprotein substrate ivermectin.Semantic proximity Read ↗

Rapid genotyping assays for the 4-base pair deletion of canine MDR1/ABCB1 gene and low frequency of the mutant allele in Border Collie dogs.Semantic proximity Read ↗

Therapeutic implications of the MDR‐1 geneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.