Article
Breed distribution of the nt230(del4) MDR1 mutation in dogs.
Veterinary journal (London, England : 1997) - 1 Jul 2011
Gramer Irina, Leidolf Regina, Döring Barbara, Klintzsch Stefanie, Krämer Eva-Maria, Yalcin Ebru, Petzinger Ernst, Geyer Joachim
Abstract excerpt
A 4-bp deletion mutation associated with multiple drug sensitivity exists in the canine multidrug resistance (MDR1) gene. This mutation has been detected in more than 10 purebred dog breeds as well as in mixed breed dogs. To evaluate the breed distribution of this mutation in Germany, 7378 dogs w...
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