Article
Homozygosity of single nucleotide polymorphisms in the 3' region of the canine estrogen receptor 1 gene is greater in Toy Poodles than in Miniature Dachshunds and Chihuahuas.
Animal science journal = Nihon chikusan Gakkaiho - 1 Jun 2011
Pathirana Indunil N, Tanaka Kakeru, Kawate Noritoshi, Tsuji Makoto, Hatoya Shingo, Inaba Toshio, Tamada Hiromichi
Abstract excerpt
Differences in the distribution of single nucleotide polymorphisms (SNPs) and haplotypes in the estrogen receptor α gene (ESR1) were examined in Miniature Dachshunds (n = 48), Chihuahuas (n = 20) and Toy Poodles (n = 18). Five DNA fragments located in the 40-kb region at the 3' end of ESR1 were amplified by polymerase chain reaction and were directly sequenced. We compared allele, genotype and estimated haplotype...
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