Article
The ESR1 gene is associated with risk for canine mammary tumours.
BMC veterinary research - 10 Apr 2013
Borge Kaja Sverdrup, Melin Malin, Rivera Patricio, Thoresen Stein Istre, Webster Matthew Thomas, von Euler Henrik, Lindblad-Toh Kerstin, Lingaas Frode
Abstract excerpt
BACKGROUND: The limited within-breed genetic heterogeneity and an enrichment of disease-predisposing alleles have made the dog a very suitable model for the identification of genes associated with risk for specific diseases. Canine mammary cancer is an example of such a disease. However, the underlying inherited risk factors for canine mammary tumours (CMTs) are still largely unknown. In this study, 52 single...
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