Article
Mitogen-activated protein kinase Hog1 mediates adaptation to G1 checkpoint arrest during arsenite and hyperosmotic stress.
Eukaryotic cell - 1 Aug 2008
Migdal Iwona, Ilina Yulia, Tamás Markus J, Wysocki Robert
Abstract excerpt
Cells slow down cell cycle progression in order to adapt to unfavorable stress conditions. Yeast (Saccharomyces cerevisiae) responds to osmotic stress by triggering G(1) and G(2) checkpoint delays that are dependent on the mitogen-activated protein kinase (MAPK) Hog1. The high-osmolarity glycerol...
Topics
- Adaptation, Physiological
- Arsenites
- Cyclin-Dependent Kinase Inhibitor Proteins
- G1 Phase
- Gene Expression Regulation, Fungal
- Genes, cdc
- Hypertonic Solutions
- Mitogen-Activated Protein Kinases
- Mutation
- Osmotic Pressure
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Teratogens