Article
Hog1 activation delays mitotic exit via phosphorylation of Net1.
Proceedings of the National Academy of Sciences of the United States of America - 21 Apr 2020
Tognetti Silvia, Jiménez Javier, Viganò Matteo, Duch Alba, Queralt Ethel, de Nadal Eulàlia, Posas Francesc
Abstract excerpt
Adaptation to environmental changes is crucial for cell fitness. In Saccharomyces cerevisiae, variations in external osmolarity trigger the activation of the stress-activated protein kinase Hog1 (high-osmolarity glycerol 1), which regulates gene expression, metabolism, and cell-cycle progression....
Topics
- Cell Cycle Proteins
- Chromosome Segregation
- DNA, Ribosomal
- Mitogen-Activated Protein Kinases
- Mitosis
- Mutation
- Nuclear Proteins
- Osmotic Pressure
- Phosphorylation
- Protein Tyrosine Phosphatases
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Telomere Homeostasis