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Article

Analysis of mitogen-activated protein kinase signaling specificity in response to hyperosmotic stress: use of an analog-sensitive HOG1 allele.

Eukaryotic cell - 1 Aug 2006

Westfall Patrick J, Thorner Jeremy

Abstract excerpt

When confronted with a marked increase in external osmolarity, budding yeast (Saccharomyces cerevisiae) cells utilize a conserved mitogen-activated protein kinase (MAPK) signaling cascade (the high-osmolarity glycerol or HOG pathway) to elicit cellular responses necessary to permit continued growth. One input that stimulates the HOG pathway requires the integral membrane protein and putative osmosensor Sho1,...

Topics

Alleles
Cell Nucleus
Gene Expression Regulation
Karyopherins
Mitogen-Activated Protein Kinases
Mutation
Osmotic Pressure
Phosphorylation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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Signal Transduction

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Identifiers

PMID: 16896207
DOI: 10.1128/EC.00037-06
PMCID: PMC1539154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16896207-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Analysis of mitogen-activated protein kinase signaling specificity in response to hyperosmotic stress: use of an analog-sensitive HOG1 allele.PMID 16896207Read ↗

The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae.Semantic proximity Read ↗

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A third osmosensing branch in Saccharomyces cerevisiae requires the Msb2 protein and functions in parallel with the Sho1 branch.Semantic proximity Read ↗

Hyperosmotic stress response and regulation of cell wall integrity in Saccharomyces cerevisiae share common functional aspects.Semantic proximity Read ↗

The osmoregulatory pathway represses mating pathway activity in Saccharomyces cerevisiae: isolation of a FUS3 mutant that is insensitive to the repression mechanism.Semantic proximity Read ↗

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