Article
Sphingolipids regulate the yeast high-osmolarity glycerol response pathway.
Molecular and cellular biology - 1 Jul 2012
Tanigawa Mirai, Kihara Akio, Terashima Minoru, Takahara Terunao, Maeda Tatsuya
Abstract excerpt
The yeast high-osmolarity glycerol response (HOG) mitogen-activated protein (MAP) kinase pathway is activated in response to hyperosmotic stress via two independent osmosensing branches, the Sln1 branch and the Sho1 branch. While the mechanism by which the osmosensing machinery activates the downstream MAP kinase cascade has been well studied, the mechanism by which the machinery senses and responds to...
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