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Article

Single molecule genotyping by TIRF microscopy.

Journal of fluorescence - 1 Sept 2008

Rüttinger Steffen, Lamarre Baptiste, Knight Alex E

Abstract excerpt

As part of a programme to develop a metrological framework for single molecule measurements in biology, we have investigated the applications of single molecule imaging to genomics. Specifically, we have developed a technique for measuring the frequencies of single nucleotide polymorphisms (SNPs) in complex or pooled samples of DNA. We believe that this technique has applications to statistical genotyping-the...

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PMID: 18551356
DOI: 10.1007/s10895-008-0386-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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