Article
Polymorphisms in the CD36 gene modulate the ability of fish oil supplements to lower fasting plasma triacyl glycerol and raise HDL cholesterol concentrations in healthy middle-aged men.
Prostaglandins, leukotrienes, and essential fatty acids - 1 Jun 2008
Madden Jacqueline, Carrero Juan J, Brunner Andreas, Dastur Neville, Shearman Cliff P, Calder Philip C, Grimble Robert F
Abstract excerpt
Five SNPs in the CD36 gene, 25444G>A, 27645del>ins, 30294G>C, -31118G>A and -33137A>G in haplotypic combinations, link to fasting plasma NEFA concentrations. Fish oil lowers TAG concentrations. The influence of CD36 SNPs on hypotriglyceridemic effects is unknown. The study examines how four of the SNPs modify the effects of fish oil on fasting plasma TAG, NEFA, glucose LDL and HDL cholesterol concentrations in...
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