Article
Replication of a Gene-Diet Interaction at CD36, NOS3 and PPARG in Response to Omega-3 Fatty Acid Supplements on Blood Lipids: A Double-Blind Randomized Controlled Trial.
EBioMedicine - 1 May 2018
Zheng Ju-Sheng, Chen Jiewen, Wang Ling, Yang Hong, Fang Ling, Yu Ying, Yuan Liping, Feng Jueping, Li Kelei, Tang Jun, Lin Mei, Lai Chao-Qiang, Li Duo
Abstract excerpt
BACKGROUND: Modulation of genetic variants on the effect of omega-3 fatty acid supplements on blood lipids is still unclear. METHODS: In a double-blind randomized controlled trial, 150 patients with type 2 diabetes (T2D) were randomized into omega-3 fatty acid group (n = 56 for fish oil and 44 for flaxseed oil) and control group (n = 50) for 180 days. All patients were genotyped for genetic variants at CD36...
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