Article
Apolipoprotein E gene polymorphism modifies fasting total cholesterol concentrations in response to replacement of dietary saturated with monounsaturated fatty acids in adults at moderate cardiovascular disease risk.
Lipids in health and disease - 23 Nov 2017
Shatwan Israa M, Weech Michelle, Jackson Kim G, Lovegrove Julie A, Vimaleswaran Karani S
Abstract excerpt
BACKGROUND: Consumption of ≤10% total energy from fat as saturated fatty acids (SFA) is recommended for cardiovascular disease risk reduction in the UK; however there is no clear guidance on the optimum replacement nutrient. Lipid-associated single-nucleotide polymorphisms (SNPs) have been shown to modify the lipid responses to dietary fat interventions. Hence, we performed a retrospective analysis in 120...
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