Article
Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci.
PLoS genetics - 1 Mar 2021
Francis Michael, Li Changwei, Sun Yitang, Zhou Jingqi, Li Xiang, Brenna J Thomas, Ye Kaixiong
Abstract excerpt
Fish oil supplementation is widely used for reducing serum triglycerides (TAGs) but has mixed effects on other circulating cardiovascular biomarkers. Many genetic polymorphisms have been associated with blood lipids, including high- and low-density-lipoprotein cholesterol (HDL-C, LDL-C), total cholesterol, and TAGs. Here, the gene-diet interaction effects of fish oil supplementation on these lipids were analyzed...
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