Article
Polymorphisms in genes involved in the triglyceride synthesis pathway and marine omega-3 polyunsaturated fatty acid supplementation modulate plasma triglyceride levels.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2013
Ouellette Catherine, Cormier Hubert, Rudkowska Iwona, Guénard Frédéric, Lemieux Simone, Couture Patrick, Vohl Marie-Claude
Abstract excerpt
BACKGROUND: Marine omega-3 (n-3) polyunsaturated fatty acids (PUFA) reduce plasma triglyceride (TG) levels. Genetic factors such as single nucleotide polymorphisms (SNPs) could be responsible for the variability of the plasma TG response to n-3 PUFA supplementation. Previous studies have demonstrated that n-3 PUFA supplementation using fish oil modified the expression levels of three genes involved in the TG...
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