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Article

ROCO kinase activity is controlled by internal GTPase function.

Science signaling - 10 Jun 2008

Weiss Bertram

Abstract excerpt

Small guanosine triphosphatases (GTPases) have long been known to control the activities of downstream protein kinases. Some members of a rather new multidomain protein family contain not only a GTPase domain of the ROC (Ras of complex protein) subtype but also a protein kinase domain, and both domains seem to cooperate with each other in the same polypeptide. Data now show that the kinase activity of one of...

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Identifiers

PMID: 18544747
DOI: 10.1126/scisignal.123pe27

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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