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Article

GTP binding and intramolecular regulation by the ROC domain of Death Associated Protein Kinase 1.

Scientific reports - 1 Jan 2012

Jebelli Joseph D, Dihanich Sybille, Civiero Laura, Manzoni Claudia, Greggio Elisa, Lewis Patrick A

Abstract excerpt

The ROCO proteins are a family of large, multidomain proteins characterised by the presence of a Ras of complex proteins (ROC) domain followed by a COR, or C-terminal of ROC, domain. It has previously been shown that the ROC domain of the human ROCO protein Leucine Rich Repeat Kinase 2 (LRRK2) controls its kinase activity. Here, the ability of the ROC domain of another human ROCO protein, Death Associated Protein...

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Source

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Identifiers

PMID: 23019516
DOI: 10.1038/srep00695
PMCID: PMC3458246

Genes

DAPK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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GTP binding and intramolecular regulation by the ROC domain of Death Associated Protein Kinase 1.PMID 23019516Read ↗

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