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Article

BDNF moderates early environmental risk factors for anxiety in mouse.

Genes, brain, and behavior - 1 Jun 2010

Carola Valeria, Gross Cornelius

Abstract excerpt

Anxiety is known to be influenced by both adverse childhood experiences and genetic susceptibility factors. A polymorphism in the brain-derived neurotrophic factor (BDNF) gene modulates the association between adverse early experiences and risk for anxiety and depression in adulthood. An animal model of this gene-by-environment risk factor is lacking. Using two different early environmental manipulations, we...

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Identifiers

PMID: 20132316
DOI: 10.1111/j.1601-183X.2010.00572.x

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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