Article
Social isolation in rats: Effects on animal welfare and molecular markers for neuroplasticity.
PloS one - 1 Jan 2020
Begni Veronica, Sanson Alice, Pfeiffer Natascha, Brandwein Christiane, Inta Dragos, Talbot Steven R, Riva Marco Andrea, Gass Peter, Mallien Anne Stephanie
Abstract excerpt
Early life stress compromises brain development and can contribute to the development of mental illnesses. A common animal model used to study different facets of psychiatric disorders is social isolation from early life on. In rats, this isolation can induce long-lasting alterations in molecular expression and in behavior. Since social isolation models severe psychiatric symptoms, it is to be expected that it...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.