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Article

Evidence supporting the match/mismatch hypothesis of psychiatric disorders.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jun 2014

Santarelli Sara, Lesuis Sylvie L, Wang Xiao-Dong, Wagner Klaus V, Hartmann Jakob, Labermaier Christiana, Scharf Sebastian H, Müller Marianne B, Holsboer Florian, Schmidt Mathias V

Abstract excerpt

Chronic stress is one of the predominant environmental risk factors for a number of psychiatric disorders, particularly for major depression. Different hypotheses have been formulated to address the interaction between early and adult chronic stress in psychiatric disease vulnerability. The match/mismatch hypothesis of psychiatric disease states that the early life environment shapes coping strategies in a manner...

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PMID: 24589292
DOI: 10.1016/j.euroneuro.2014.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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