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Article

The impact of environmental enrichment on sex-specific neurochemical circuitries - effects on brain-derived neurotrophic factor and the serotonergic system.

Neuroscience - 18 Sept 2012

Chourbaji S, Hörtnagl H, Molteni R, Riva M A, Gass P, Hellweg R

Abstract excerpt

Experimental evidence in mice indicates that environmental conditions affect females and males differently. However, in a recent study analyzing the heterozygous mutation of brain-derived neurotrophic factor (BDNF), both sexes presented a similar emotional phenotype, which became obvious only under impoverished, but not in enriched conditions suggesting an "enrichment-induced" rescue. To investigate the basis of...

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Source

Identifiers

PMID: 22710068
DOI: 10.1016/j.neuroscience.2012.06.016

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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