Structural requirements for localization and activation of protein kinase C mu (PKC mu) at the Golgi compartment.

doi:10.1083/jcb.200110047

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Article

Structural requirements for localization and activation of protein kinase C mu (PKC mu) at the Golgi compartment.

The Journal of cell biology - 7 Jan 2002

Hausser Angelika, Link Gisela, Bamberg Linda, Burzlaff Annett, Lutz Sylke, Pfizenmaier Klaus, Johannes Franz-Josef

Abstract excerpt

We here describe the structural requirements for Golgi localization and a sequential, localization-dependent activation process of protein kinase C (PKC) mu involving auto- and transphosphorylation. The structural basis for Golgi compartment localization was analyzed by confocal microscopy of HeL...

Topics

Blotting, Western
Cell Line
Enzyme Activation
Golgi Apparatus
Green Fluorescent Proteins
HeLa Cells
Humans
Intracellular Membranes
Luminescent Proteins
Microscopy, Confocal
Microscopy, Fluorescence
Models, Biological
Mutation
Phosphorylation
Phosphoserine

Source

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Identifiers

PMID: 11777941
DOI: 10.1083/jcb.200110047
PMCID: PMC2173578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-11777941-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Protein Binding

Protein Kinase C

Protein Structure, Tertiary