Article
Structural requirements for localization and activation of protein kinase C mu (PKC mu) at the Golgi compartment.
The Journal of cell biology - 7 Jan 2002
Hausser Angelika, Link Gisela, Bamberg Linda, Burzlaff Annett, Lutz Sylke, Pfizenmaier Klaus, Johannes Franz-Josef
Abstract excerpt
We here describe the structural requirements for Golgi localization and a sequential, localization-dependent activation process of protein kinase C (PKC) mu involving auto- and transphosphorylation. The structural basis for Golgi compartment localization was analyzed by confocal microscopy of HeLa cells expressing various PKC mu-green fluorescent protein fusion proteins costained with the Golgi...
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