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Article

Structural function of MIP/aquaporin 0 in the eye lens; genetic defects lead to congenital inherited cataracts.

Handbook of experimental pharmacology - 1 Jan 2009

Chepelinsky Ana B

Abstract excerpt

Aquaporin 0 (AQP0) was originally characterized as a membrane intrinsic protein, specifically expressed in the lens fibers of the ocular lens and designated MIP, for major intrinsic protein of the lens. Once the gene was cloned, an internal repeat was identified, encoding for the amino acids Asp-...

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Topics

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Share to Lens, Crystalline
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Processing, Post-Translational

Source

Identifiers

PMID: 19096783
DOI: 10.1007/978-3-540-79885-9_14

Genes

MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19096783-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Structural function of MIP/aquaporin 0 in the eye lens; genetic defects lead to congenital inherited cataracts.PMID 19096783Read ↗

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Congenital progressive polymorphic cataract caused by a mutation in the major intrinsic protein of the lens, MIP (AQP0).Semantic proximity Read ↗

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A Novel Missense Mutation in the Gene Encoding Major Intrinsic Protein (MIP) in a Giant Panda with Unilateral Cataract FormationSemantic proximity Read ↗

Lens transcriptome profile during cataract development in Mip-null mice.Semantic proximity Read ↗

A novel nonsense mutation in the MIP gene linked to congenital posterior polar cataracts in a Chinese family.Semantic proximity Read ↗

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A novel missense mutation in the gene encoding major intrinsic protein (MIP) in a Giant panda with unilateral cataract formationSemantic proximity Read ↗

The relationship between major intrinsic protein genes and cataract.Semantic proximity Read ↗

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