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Article

A novel nonsense mutation in the MIP gene linked to congenital posterior polar cataracts in a Chinese family.

PloS one - 1 Jan 2015

Song Zixun, Wang Lianqing, Liu Yaping, Xiao Wei

Abstract excerpt

PURPOSE: To detect the causative mutation for congenital posterior polar cataracts in a five-generation Chinese family and further explore the potential pathogenesis of this disease. METHODS: Coding exons, with flanking sequences of five candidate genes, were screened using direct DNA sequencing. The identified mutations were confirmed by restriction fragment length polymorphism (RFLP) analysis. A full-length...

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Identifiers

PMID: 25803033
DOI: 10.1371/journal.pone.0119296
PMCID: PMC4372439

Genes

MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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