Article
Host range specificity of polyomavirus EC mutants in mouse embryonal carcinoma and embryonal stem cells and preimplantation embryos.
Journal of virology - 1 Jun 1991
Mélin F, Kemler R, Kress C, Pinon H, Blangy D
Abstract excerpt
New polyomavirus mutants (PyEC-C) selected on LT1 cells and exhibiting a strong cytopathic effect in all embryonal carcinoma (EC) cell lines tested have been isolated. They were derived by a sequence duplication event from a new multiadapted mutant isolated in PCC4 cells. A quantitative analysis...
Topics
- Animals
- Blastocyst
- Cytopathogenic Effect, Viral
- DNA Replication
- DNA, Viral
- Embryonic Development
- Female
- Gene Expression
- Mice
- Mice, Inbred C57BL
- Multigene Family
- Mutation
