Article
Viral genomes maintained extrachromosomally in hamster polyomavirus-induced lymphomas display a cell-specific replication in vitro.
Journal of virology - 1 Dec 1993
de La Roche Saint André C, Mazur S, Feunteun J
Abstract excerpt
Hamster polyomavirus causes lymphomas when injected into newborn Syrian hamsters. Large amounts of extrachromosomal viral genomes are accumulated in the lymphoma cells. These genomes are characterized by deletions affecting the late coding region as well as a specific part of the noncoding regula...
Topics
- Animals
- Base Sequence
- Cells, Cultured
- Chromosome Mapping
- Cricetinae
- DNA Replication
- DNA-Binding Proteins
- Extrachromosomal Inheritance
- Fibroblasts
- Gene Rearrangement
- Genome, Viral
- Lymphoma
- Mesocricetus
- Molecular Sequence Data
- Mutation
- Polyomavirus
- Regulatory Sequences, Nucleic Acid
- Sequence Deletion