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Article

Reduced Polyomavirus DNA replication as a consequence of a late-region deletion that results in early mRNA instability.

Virus research - 1 Jul 1991

Risuleo G, Melucci-Vigo G, Magnusson G

Abstract excerpt

A Polyomavirus mutant with a 504 base pair deletion downstream of the polyadenylation signal for the early genes was constructed in vitro. This mutant showed a reduced synthesis of viral DNA. In cotransfection experiments, this defect was complemented by the presence of a wild-type genome. To define the sequences involved in the determination of this phenotype, a set of viral mutants was constructed. The...

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Identifiers

PMID: 1659059
DOI: 10.1016/0168-1702(91)90106-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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