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Article

S(mu) mutation patterns suggest different progression pathways in follicular lymphoma: early direct or late from FL progenitor cells.

Blood - 1 Sept 2008

Ruminy Philippe, Jardin Fabrice, Picquenot Jean-Michel, Parmentier Françoise, Contentin Nathalie, Buchonnet Gérard, Tison Sandrine, Rainville Vinciane, Tilly Hervé, Bastard Christian

Abstract excerpt

Follicular lymphoma (FL) is a B-cell malignancy characterized by the t(14;18) translocation. Although sensitive to treatment, the disease remains incurable and the reason why tumor cells invariably evade treatment, leading to clinical relapse, is still unknown. Here, we tracked the clonal history of tumor cells by studying mutations introduced by activation-induced cytidine deaminase on the switch mu region of...

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Share to AICDA (Activation-Induced Cytidine Deaminase)
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Identifiers

PMID: 18515657
DOI: 10.1182/blood-2007-11-124560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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