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Article

From genetics to the clinic: a translational perspective on follicular lymphoma.

Nature reviews. Cancer - 1 Apr 2018

Huet Sarah, Sujobert Pierre, Salles Gilles

Abstract excerpt

Follicular lymphoma (FL) is the most frequent indolent B cell lymphoma and is still considered to be incurable. In recent years, whole-exome sequencing studies of large cohorts of patients have greatly improved our knowledge of the FL mutational landscape. Moreover, the prolonged evolution of this disease has enabled some insights regarding the early pre-lymphoma lesions as well as the clonal evolution after...

Topics

Antineoplastic Agents
Cell Proliferation
Cell Survival
Chromatin
DNA Methylation
Epigenesis, Genetic
Humans
Immune Evasion
Lymphoma, Follicular
Molecular Targeted Therapy
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Translational Research, Biomedical

Source

Identifiers

PMID: 29422597
DOI: 10.1038/nrc.2017.127

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