Article
Tumor suppressors in follicular lymphoma.
Leukemia & lymphoma - 1 Jul 2015
Graham Cassandra, LeBrun David P
Abstract excerpt
Follicular lymphoma (FL) is the most common indolent lymphoma. The vast majority of cases are associated with the chromosome translocation t(14;18), a somatic rearrangement that leads to constitutive expression of the anti-apoptotic BCL2 protein. Although t(14;18) clearly represents an important early event in FL pathogenesis, abundant evidence indicates that it is not sufficient. In particular, the recent...
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