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Follicular lymphoma-like B cells in healthy individuals: a novel intermediate step in early lymphomagenesis

16 Oct 2006

Abstract excerpt

Follicular lymphoma is one of the most common adult lymphoma, and remains virtually incurable despite its relatively indolent nature. t(14;18)(q32;q21) translocation, the genetic hallmark and early initiating event of follicular lymphoma (FL) pathogenesis, is also present at low frequency in the peripheral blood of healthy individuals. It has long been assumed that in healthy individuals t(14;18) is carried by...

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PMID: 17043145
DOI: 10.1084/jem.20061292

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