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Article

P4-ATPase requirement for AP-1/clathrin function in protein transport from the trans-Golgi network and early endosomes.

Molecular biology of the cell - 1 Aug 2008

Liu Ke, Surendhran Kavitha, Nothwehr Steven F, Graham Todd R

Abstract excerpt

Drs2p is a resident type 4 P-type ATPase (P4-ATPase) and potential phospholipid translocase of the trans-Golgi network (TGN) where it has been implicated in clathrin function. However, precise protein transport pathways requiring Drs2p and how it contributes to clathrin-coated vesicle budding remain unclear. Here we show a functional codependence between Drs2p and the AP-1 clathrin adaptor in protein sorting at...

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Identifiers

PMID: 18508916
DOI: 10.1091/mbc.e08-01-0025
PMCID: PMC2488278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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